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HIC1
An Error has occured retrieving Wikidata item for infobox HIC1 (HIC ZBTB transcriptional repressor 1) هوَ بروتين يُشَفر بواسطة جين HIC1 في الإنسان.[1]
الوظيفة
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ "Entrez Gene: HIC1 hypermethylated in cancer 1". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Chopin V، Leprince D (2006). "[Chromosome arm 17p13.3: could HIC1 be the one ?]". Med Sci (Paris). ج. 22 ع. 1: 54–61. DOI:10.1051/medsci/200622154. PMID:16386221.
- Wales MM، Biel MA، el Deiry W، وآخرون (1995). "p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3". Nat. Med. ج. 1 ع. 6: 570–7. DOI:10.1038/nm0695-570. PMID:7585125.
- Fujii H، Biel MA، Zhou W، وآخرون (1998). "Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer". Oncogene. ج. 16 ع. 16: 2159–64. DOI:10.1038/sj.onc.1201976. PMID:9572497.
- Deltour S، Guerardel C، Stehelin D، Leprince D (1999). "The carboxy-terminal end of the candidate tumor suppressor gene HIC-1 is phylogenetically conserved". Biochim. Biophys. Acta. ج. 1443 ع. 1–2: 230–2. DOI:10.1016/s0167-4781(98)00219-x. PMID:9838134.
- Deltour S، Guerardel C، Leprince D (2000). "Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: the case of HIC-1 and gammaFBP-B". Proc. Natl. Acad. Sci. U.S.A. ج. 96 ع. 26: 14831–6. DOI:10.1073/pnas.96.26.14831. PMC:24733. PMID:10611298.
- Guerardel C، Deltour S، Pinte S، وآخرون (2001). "Identification in the human candidate tumor suppressor gene HIC-1 of a new major alternative TATA-less promoter positively regulated by p53". J. Biol. Chem. ج. 276 ع. 5: 3078–89. DOI:10.1074/jbc.M008690200. PMID:11073960.
- Deltour S، Pinte S، Guérardel C، Leprince D (2001). "Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1". Biochem. Biophys. Res. Commun. ج. 287 ع. 2: 427–34. DOI:10.1006/bbrc.2001.5624. PMID:11554746.
- Deltour S، Pinte S، Guerardel C، وآخرون (2002). "The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif". Mol. Cell. Biol. ج. 22 ع. 13: 4890–901. DOI:10.1128/MCB.22.13.4890-4901.2002. PMC:133903. PMID:12052894.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Cardoso C، Leventer RJ، Ward HL، وآخرون (2003). "Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3". Am. J. Hum. Genet. ج. 72 ع. 4: 918–30. DOI:10.1086/374320. PMC:1180354. PMID:12621583.
- Rathi A، Virmani AK، Harada K، وآخرون (2004). "Aberrant methylation of the HIC1 promoter is a frequent event in specific pediatric neoplasms". Clin. Cancer Res. ج. 9 ع. 10 Pt 1: 3674–8. PMID:14506157.
- Waha A، Waha A، Koch A، وآخرون (2004). "Epigenetic silencing of the HIC-1 gene in human medulloblastomas". J. Neuropathol. Exp. Neurol. ج. 62 ع. 11: 1192–201. PMID:14656076.
- Lindsey JC، Lusher ME، Anderton JA، وآخرون (2004). "Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling". Carcinogenesis. ج. 25 ع. 5: 661–8. DOI:10.1093/carcin/bgh055. PMID:14688019.
- Pinte S، Guérardel C، Deltour-Balerdi S، وآخرون (2004). "Identification of a second G-C-rich promoter conserved in the human, murine and rat tumor suppressor genes HIC1". Oncogene. ج. 23 ع. 22: 4023–31. DOI:10.1038/sj.onc.1207504. PMID:15007385.
- Pinte S، Stankovic-Valentin N، Deltour S، وآخرون (2004). "The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties". J. Biol. Chem. ج. 279 ع. 37: 38313–24. DOI:10.1074/jbc.M401610200. PMID:15231840.
- Chen W، Cooper TK، Zahnow CA، وآخرون (2004). "Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis". Cancer Cell. ج. 6 ع. 4: 387–98. DOI:10.1016/j.ccr.2004.08.030. PMID:15488761.
- Britschgi C، Rizzi M، Grob TJ، وآخرون (2006). "Identification of the p53 family-responsive element in the promoter region of the tumor suppressor gene hypermethylated in cancer 1". Oncogene. ج. 25 ع. 14: 2030–9. DOI:10.1038/sj.onc.1209240. PMID:16301995.
- Valenta T، Lukas J، Doubravska L، وآخرون (2006). "HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies". EMBO J. ج. 25 ع. 11: 2326–37. DOI:10.1038/sj.emboj.7601147. PMC:1478201. PMID:16724116.
- Stankovic-Valentin N، Verger A، Deltour-Balerdi S، وآخرون (2006). "A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP". FEBS J. ج. 273 ع. 13: 2879–90. DOI:10.1111/j.1742-4658.2006.05301.x. PMID:16762039.